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MDPI AG
Prevalence and Clinical Management of Adrenal Tumour-Related Hyperandrogenism: A Narrative Review
Hyperandrogenism is a condition in which the levels of androgen hormones in the blood are significantly increased and could be of an adrenal or ovarian origin. The adrenal androgens, normally secreted by the zona reticularis, are steroid hormones with weak androgen activity. The causes of hyperandrogenism are diverse and could be endogenous and exogenous. Androgen excess affecting different tissues and organs results in clinical features such as acne, hirsutism, virilization, and reproductive dysfunction...
Preuzmite dokument 2024 Alfredo Pontecorvi , Ljubica Batkoska , Emanuela Traini , Domenico Milardi , Carmine Bruno , Sanja Medenica , Dusan Zivanovic
Research Square Platform LLC
Xantho-Granulomatous Hypophysitis: Analysis Of Clinical, Biochemical, Radiological And Etiological Characteristics
Abstract Introduction: Xanthogranulomas (XG) are chronic inflammatory lesions caused by accumulation of lipid laden macrophages with granuloma formation, usually secondary to hemorrhage, infarction or necrosis upon existing neoplasm or cyst. Primary sellar xanthogranulomas are rare and may represent a stage in xanthomatous hypophysitis (XH) evolution.Aim: To analyze clinical presentation, hormonal, radiological and histological features of patients diagnosed with pituitary xanthomatous and...
Preuzmite dokument 2022 Zvezdana Jemuovic , Dragana Miljic , Danica Grujicic , Mirjana Doknic , Toplica Milojevic , Sandra Pekic , Marko Stojanovic , Marina Nikolic Djurovic , Sanja Medenica , Sasa Ilic , Emilija Manojlovic Gacic , Mihailo Milicevic , Nevena Radic , Jovan Jovanovic , Milan Petakov ... Pogledajte sve
Wiley
Female infertility in the era of obesity: The clash of two pandemics or inevitable consequence?
AbstractObesity is an epidemic that has led to a rise in the incidence of many comorbidities: among others, reduced fertility is often under‐evaluated in clinical practice. The mechanisms underlying the link between reduced fertility and obesity are numerous, with insulin resistance, hyperglycaemia and the frequent coexistence of polycystic ovary syndrome being the most acknowledged. However, several other factors concur, such as gut microbiome alterations, low‐grade chronic inflammation and oxidative...
Preuzmite dokument 2022 Lucio Gnessi , Maria Elena Spoltore , Rossella Mazzilli , Ljiljana V. Marina , Paulina Ormazabal , Antoan Stefan Sojat , Sanja Medenica , Antongiulio Faggiano , Mikiko Watanabe
Hindawi Limited
The Role of Cell and Gene Therapies in the Treatment of Infertility in Patients with Thyroid Autoimmunity
There is a rising incidence of infertility worldwide, and many couples experience difficulties conceiving nowadays. Thyroid autoimmunity (TAI) is recognized as one of the major female infertility causes related to a diminished ovarian reserve and potentially impaired oocyte maturation and embryo development, causing adverse pregnancy outcomes. Growing evidence has highlighted its impact on spontaneously achieved pregnancy and pregnancy achieved by in vitro fertilization. Despite the influence of...
Preuzmite dokument 2022 Dzihan Abazovic , Gaspare Cucinella , Aleksa Begovic , Simona Zaami , Giuseppe Gullo , Aleksandar Ljubić , Jovana Vukovic , Sanja Medenica
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