Bentham Science Publishers Ltd.
Therapeutic Potential of Sodium-glucose Co-transporter-2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists for Patients with Acute Coronary Syndrome: A Review of Clinical Evidence
:
Atherosclerotic Cardiovascular Disease (ASCVD) is still one of the leading causes of death globally,
with Coronary Artery Disease (CAD) being the most prevalent form of ASCVD. Patients with type 2 Diabetes
Mellitus (DM) experience an increased risk for ASCVD during the disease course, with CAD being the
most common cause of death among affected individuals, resulting in shorter life expectancy and increased
morbidity among survivors. Recently, 2 novel classes of anti-diabetic drugs, namely Sodium-Glucose...
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2024
Paschalis Karakasis
,
Manfredi Rizzo
,
Nikolaos Fragakis
,
Theocharis Koufakis
,
Michael Doumas
,
Aleksandra Klisic
,
Dimitrios Patoulias
,
George Kassimis
Wiley
Effects of glucagon‐like peptide‐1 receptor agonists on glycated haemoglobin and continuous glucose monitoring metrics as adjunctive therapy to insulin in adults with type 1 diabetes: A meta‐analysis of randomized controlled trials
AbstractAimsTo conduct a meta‐analysis of randomized controlled trials (RCTs) to evaluate the effect of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) on glycated haemoglobin (HbA1c) and continuous glucose monitoring (CGM) metrics as an adjunct to insulin therapy in adults with type 1 diabetes mellitus (T1D).MethodsA systematic literature search was conducted through Medline (via PubMed), Cochrane Library, and Google Scholar up to 27 May 2024. Dual‐independent study selection, data extraction,...
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2024
Paschalis Karakasis
,
Fotios Barkas
,
Theocharis Koufakis
,
Michael Doumas
,
Nikolaos Papanas
,
Aleksandra Klisic
,
Djordje S. Popovic
,
Milena Mitrovic
,
Dimitrios Patoulias
Termedia Sp. z.o.o.
Interleukins: pathophysiological role in acute pancreatitis
Acute pancreatitis (AP) is a common inflammatory state characterized by a clinical course that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins (ILs) are biologically active glycoproteins primarily produced by macrophages and lymphocytes. According to the literature, there are many ILs. However, this article represents a summary of the role of ILs in AP, such as IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12, IL-13, IL-14, IL-15,...
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2024
Saima Sharif
,
Saira Rafaqat
,
Amir Hossein Behnoush
,
Aleksandra Klisic
,
Dimitrios Patoulias
MDPI AG
The Association between Coagulation and Atrial Fibrillation
The existing literature highlights the presence of numerous coagulation factors and markers. Elevated levels of coagulation factors are associated with both existing and newly diagnosed cases of atrial fibrillation (AF). However, this article summarizes the role of coagulation in the pathogenesis of AF, which includes fibrinogen and fibrin, prothrombin, thrombomodulin, soluble urokinase plasminogen activator receptor, von Willebrand factor, P-selectin, D-dimer, plasminogen activator inhibitor-1,...
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2024
Saima Sharif
,
Sanja Gluscevic
,
Saira Rafaqat
,
Aleksandra Klisic
,
Dimitrios Patoulias
