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MDPI AG
Cardiometabolic Risk Factors Related to Atrial Fibrillation and Metabolic Syndrome in the Pakistani Population
Background and Objectives: This study aimed to examine the relationship between cardiometabolic risk factors and atrial fibrillation (AF) and the simultaneous presence of AF and metabolic syndrome (MetS) in the Pakistani population. Materials and Methods: A total of 690 subjects were enrolled (n = 230 patients with AF, n = 230 patients with AF and MetS, and n = 230 controls). The associations between cardiometabolic parameters and AF with and without MetS were analyzed by univariable and multivariable...
Preuzmite dokument 2024 Saima Sharif , Shagufta Naz , Filiz Mercantepe , Sanja Gluscevic , Saira Rafaqat , Aleksandra Klisic , Ana Ninic
Termedia Sp. z.o.o.
Interleukins: pathophysiological role in acute pancreatitis
Acute pancreatitis (AP) is a common inflammatory state characterized by a clinical course that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins (ILs) are biologically active glycoproteins primarily produced by macrophages and lymphocytes. According to the literature, there are many ILs. However, this article represents a summary of the role of ILs in AP, such as IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12, IL-13, IL-14, IL-15,...
Preuzmite dokument 2024 Saima Sharif , Saira Rafaqat , Amir Hossein Behnoush , Aleksandra Klisic , Dimitrios Patoulias
MDPI AG
Interleukins: Pathogenesis in Non-Alcoholic Fatty Liver Disease
Inflammatory cytokines have been implicated as crucial contributors to the onset and progression of non-alcoholic fatty liver disease (NAFLD). The exact mechanisms by which interleukins (ILs) contribute to NAFLD may vary, and ongoing research is aimed at understanding the specific roles of different ILs in the pathogenesis of this condition. In addition, variations in environmental factors and genetics in each individual can influence the onset and/or progression of NAFLD. The lack of clinical studies...
Preuzmite dokument 2024 Filiz Mercantepe , Sana Rafaqat , Sanja Gluscevic , Saira Rafaqat , Aleksandra Klisic
MDPI AG
The Association between Coagulation and Atrial Fibrillation
The existing literature highlights the presence of numerous coagulation factors and markers. Elevated levels of coagulation factors are associated with both existing and newly diagnosed cases of atrial fibrillation (AF). However, this article summarizes the role of coagulation in the pathogenesis of AF, which includes fibrinogen and fibrin, prothrombin, thrombomodulin, soluble urokinase plasminogen activator receptor, von Willebrand factor, P-selectin, D-dimer, plasminogen activator inhibitor-1,...
Preuzmite dokument 2024 Saima Sharif , Sanja Gluscevic , Saira Rafaqat , Aleksandra Klisic , Dimitrios Patoulias
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