This paper examines how geoheritage assessment and landscape interpretation can inform geotourism planning and the exploratory identification of place-based innovation opportunities. The study area centres on the Vranje Basin and includes geosite Vražji Kamen in the Pčinja River Valley as a complementary case. Five purposively selected geosites, Vranjska Banja, Markovo Kale, Kazandjol Canyon, Vražji Kamen, and Pržar Viewpoint, were evaluated and compared using a Modified Geosite Assessment Model (M-GAM). The results show generally high scientific, scenic, and educational values, but considerable differences in tourism-related support, particularly in organised visits, on-site interpretation, visitor facilities, and guiding. Geosites Vražji Kamen and Vranjska Banja have nearly identical leading Main Values, whereas Vranjska Banja has the most balanced overall profile. An equal-weight comparison yielded similar site profiles and the same Additional Values ranking, although the adopted visitor-importance factor has not been locally validated. In a separate analytical step, the M-GAM results and documented contextual evidence were compared with the official Serbian 4S priorities: Food for the Future, Information and Communication Technologies, Future Machines and Manufacturing Systems, and Creative Industries. Since tourism is not an official 4S priority, it was considered a cross-sectoral activity that may connect geosite interpretation and visitor-service activities. Under the stated inclusion criteria, candidate linkages between individual geosites and official 4S domains were formulated for subsequent stakeholder assessment. The M-GAM/4S crosswalk distinguishes direct assessment results, contextual evidence, and author-derived development hypotheses. The proposed activities include digital hydrothermal interpretation at Vranjska Banja, digital storytelling at Markovo Kale, field-based geoscience education at Kazandjol Canyon, conservation-sensitive interpretation at Vražji Kamen, and GIS-based landscape interpretation at Pržar. Their feasibility should be examined through stakeholder consultation, the Entrepreneurial Discovery Process, and site-specific conservation assessment.
