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Interleukins: pathophysiological role in acute pancreatitis
Acute pancreatitis (AP) is a common inflammatory state characterized by a clinical course that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins (ILs) are biologically active glycoproteins primarily produced by macrophages and lymphocytes. According to the literature, there are many ILs. However, this article represents a summary of the role of ILs in AP, such as IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12, IL-13, IL-14, IL-15,...
Preuzmite dokument
2024
Saima Sharif
,
Saira Rafaqat
,
Amir Hossein Behnoush
,
Aleksandra Klisic
,
Dimitrios Patoulias
MDPI AG
The Association between Coagulation and Atrial Fibrillation
The existing literature highlights the presence of numerous coagulation factors and markers. Elevated levels of coagulation factors are associated with both existing and newly diagnosed cases of atrial fibrillation (AF). However, this article summarizes the role of coagulation in the pathogenesis of AF, which includes fibrinogen and fibrin, prothrombin, thrombomodulin, soluble urokinase plasminogen activator receptor, von Willebrand factor, P-selectin, D-dimer, plasminogen activator inhibitor-1,...
Preuzmite dokument
2024
Saima Sharif
,
Sanja Gluscevic
,
Saira Rafaqat
,
Aleksandra Klisic
,
Dimitrios Patoulias
MDPI AG
Redox Status and Telomere–Telomerase System Biomarkers in Patients with Acute Myocardial Infarction Using a Principal Component Analysis: Is There a Link?
In the present study, we examined redox status parameters in arterial and venous blood samples, its potential to predict the prognosis of acute myocardial infarction (AMI) patients assessed through its impact on the comprehensive grading SYNTAX score, and its clinical accuracy. Potential connections between common blood biomarkers, biomarkers of redox status, leukocyte telomere length, and telomerase enzyme activity in the acute myocardial infarction burden were assessed using principal component...
Preuzmite dokument
2023
Milica Stefanović
,
Srdjan Kafedžić
,
Aleksandar N. Nešković
,
Saša Hinić
,
Ivan Ilić
,
Barbara Ostanek
,
Miron Sopić
,
Nataša Bogavac-Stanojević
,
Janja Marc
,
Marija Zdravković
,
Jelena Kotur-Stevuljevic
,
Aleksandra Klisic
,
Aleksandra Vukašinović
... Pogledajte sve
Bentham Science Publishers Ltd.
The Link between miRNAs and PCKS9 in Atherosclerosis
Abstract:
Cardiovascular disease (CDV) represents the major cause of death globally.
Atherosclerosis, as the primary cause of CVD, is a chronic immune-inflammatory disorder
with complex multifactorial pathophysiology encompassing oxidative stress, enhanced
immune-inflammatory cascade, endothelial dysfunction, and thrombosis. An initiating
event in atherosclerosis is the subendothelial accumulation of low-density lipoprotein
(LDL), followed by the localization of macrophages to fatty deposits on...
Preuzmite dokument
2023
Jasjit Suri
,
Esma Isenovic
,
Manfredi Rizzo
,
Mirjana Macvanin
,
Zoran Gluvic
,
Mia Manojlovic
,
Aleksandra Klisic