16.10.2026
openRxiv
Quantifying optimal AWaRe antibiotic use patterns in hospitals with a new benchmarking tool applied to cross-sectional point prevalence survey data from 10 countries
Background: Both over- and under-antibiotic use pose major global health challenges, yet there is no consensus on how to quantify deviations from optimal prescribing or set evidence-based targets. We developed a benchmarking tool for inpatient antibiotic use and evaluated its application in 10 countries.
Methods: We developed decision-tree models to estimate expected empiric antibiotic use for 11 indications, based on the WHO AWaRe book for two age groups: 28 days to 12 years and >12 years. We...
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Ben S Cooper
,
Mari Rose De Los Reyes
,
,
Herberth Maldonado
,
Ana Paula Matos Porto
,
David C Banda
,
Jemelyn Garcia
,
Silvia Figueiredo Costa
,
Jafar Soltani
,
Yuliya Belkova
,
Maja Raicevic
,
Erika Vlieghe
,
Michael Sharland
,
Ann Versporten
,
Cherry Lim
,
Milena Lopicic
,
Myo Maung Maung Swe
,
Ines Pauwel
,
Svetlana Rachina
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Preuzmite dokument
2026
14.10.2026
Frontiers Media SA
Availability and reimbursement of fixed-dose combination medicines for hypertension treatment in Central and Eastern Europe
Introduction
Fixed-dose combinations (FDCs) represent an important strategy in modern pharmacotherapy and are particularly beneficial in the treatment of chronic conditions such as hypertension because they reduce pill burden and may improve patient adherence to therapy.
Objectives
The primary objective of this study was to compare reimbursement, pricing, and availability policies...
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Paweł Kawalec
,
Jana Skoupa
,
Natasa Duborija-Kovacevic
,
Pero Draganić
,
Elena Chitan
,
Kristina Garuoliene
,
Tomas Tesar
,
Arturs Praskilevics
,
Nikola Stefanovic
,
Przemysław Holko
,
Michał Owca
,
Tamás Ágh
,
Iris Hoxha
,
Agnes Männik
,
Ioana Bianchi-Manaila
,
Rafał Nowak
,
Alexandra Savova
,
Ljubica Shuturkova
,
Zoltán Kaló
... Pogledajte sve
Preuzmite dokument
2026