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MDPI AG
Donepezil Derivatives as Potential Dual AChE/BChE Inhibitors: Fragment-Based Design, AI-Assisted Retrosynthesis, and In Silico Evaluation
Alzheimer’s disease (AD) is a complex neurodegenerative condition marked by a gradual decline in cognitive abilities, a reduction in acetylcholine (ACh) levels, and the accumulation of β-amyloid (Aβ) plaques. In a healthy brain, approximately 80% of ACh is broken down by acetylcholinesterase (AChE). Meanwhile, butyrylcholinesterase (BChE) serves a supportive function, gaining significance as AChE activity diminishes during the progression of Alzheimer’s disease. Modern therapeutic approaches focus...
Preuzmite dokument
2026
Ana Antonijević
,
Miona Glišić
,
Svetlana Jeremić
,
Marko Antonijević
,
Jelena Đorović Jovanović
,
Marijana Stanojević Pirković
Universidad del Zulia
Principal component analysis and multidimensional scaling of the morphological traits of olive clones
This study analyzed the morphological traits of the Žutica olive variety, assessing its variability through statistical methods. Principal component analysis (PCA) identified the first three components as having the greatest influence on the grouping of Žutica clones. Fruit and endocarp length, width, and weight, as well as pulp weight, were associated with PC1, while the shape index of both fruit and endocarp was linked to PC2. PC3 included the leaf shape index, internode length, pulp percentage,...
Preuzmite dokument
2026
Tatjana Perović
,
Mirjana Adakalić
,
Biljana Lazović
Oxford University Press (OUP)
Radiation hazard indices associated with natural radioactivity in building materials in Montenegro
Abstract
Eleven building materials (95 samples in total) have been analyzed for 226Ra, 228Ra (232Th series), and 40K activity using High Purity Germanium (HPGe) spectrometry, and concentrations are found to be in the range (2.2–549), (0.3–161), and (2.7–1034) Bq kg−1, respectively. Statistical analyses showed a moderate positive linear correlation between 226Ra and 228Ra, and significant differences in the mean radionuclide concentrations among ceramic tile, brick, granite, and...
Preuzmite dokument
2026
Tomislav Anđelić
,
Nevenka M Antović
MDPI AG
A Portable Solar-Powered Edge-AI System for Livestock Monitoring in Off-Grid Mountain Pastures: System Design and Field Validation
Highland pastures in Montenegro, known as katuns, are seasonal settlements without grid power or network coverage and which are located where conventional monitoring is unfeasible. This study presents a solar-powered, off-grid system for livestock and environmental monitoring. It integrates, into a single portable unit, a solar power station, an edge-AI computer, a camera, environmental sensors, a LoRaWAN gateway, and a cellular router for backhaul. All parts are pre-wired in a modular enclosure,...
Preuzmite dokument
2026
Janko Kaljević
,
Dejan Drajić
,
Dejan Babic
,
Ivan Jovovic
,
Tomo Popovic
Faculty of Philology - University of Montenegro
MESIJANSKE IDEJE I ULOGA INTELIGENCIJE U ROMANU DMITRIJA MEREŠKOVSKOG ANTIHRIST. PETAR I ALEKSEJ
Problemu i fenomenu ruske inteligencije Dmitrij Mereškovski je
posvećivao pažnju u različitim djelima, i ova tema je sa prekidima veoma
frekventna u njegovom stvaralaštvu, počev od brojnih publicističkih tekstova,
preko istoriozofskog romana Antihrist. Petar i Aleksej (1905), pa do Nadirućeg
prostaka(1906). Dijelom smo posvetili pažnju genezi pojma inteligencije i
inteligenta u kontekstu ruske kulture ukazujući na bitnije razlike u odnosu na
pojam i fenomen intelektualca na Zapadu, referišući se...
Preuzmite dokument
2026
Neda Andrić
Faculty of Philology - University of Montenegro
DUBRAVKA ĐURIĆ’S POETICS OF HOPE IN THE POLITICS OF HOPE (AFTER THE WAR) (2024)
Dubravka Đurić’s collection of poetry, The Politics of Hope (After the
War), features a selection of works dating from 1982 to 2024. The anthology is
edited and translated into English by Biljana D. Obradović, with an introductory
foreword authored by Charles Bernstein. Đurić’s book received prestigious
recognition from the North American Society for Serbian Studies (NASSS) in
2024 for its exceptional cultural achievement, while, in his review, Mark
Wallace argues that it is one of Southeast Europe’s...
Preuzmite dokument
2026
Marija Krivokapić