Digital platoform

MDPI AG

The Pond Snails of the Genus Radix (Gastropoda, Lymnaeidae) in Issyk-Kul Lake (Central Asia), with a Review of Radix in Ancient Tectonic Lakes of the World

Lake Issyk-Kul, situated in the Republic of Kyrgyzstan, is one of the largest lakes in Central Asia. Though this brackish-water basin holds only a species-poor fauna of molluscs, the number of species inhabiting Issyk-Kul and their true taxonomic position remain unsatisfactorily studied. Most nominal species of Mollusca reported from Issyk-Kul are known from empty shells only and have never been studied molecularly. This study reports the results of a revision of the genus Radix (Gastropoda:Hygrophila:Lymnaeidae)...

Preuzmite dokument 2025 Ivan N. Bolotov , Olga V. Aksenova , Maxim V. Vinarski , Vladimir Pešić , Victor R. Alekseev , Alexander V. Kondakov , Irina S. Khrebtova , Vitaly M. Spitsyn

MDPI AG

The Potential Role of sPD-L1 as a Predictive Biomarker in EGFR-Positive Non-Small-Cell Lung Cancer

Background/Objectives: A significant breakthrough in non-small-cell lung cancer (NSCLC) treatment has occurred with the introduction of targeted therapies and immunotherapy. However, not all patients treated with these therapies would respond to treatment, and patients who respond to treatment would acquire resistance at some time point. This is why we need new biomarkers that can predict response to therapy. The aim of this study was to investigate whether soluble programmed cell death-ligand 1...

Preuzmite dokument 2025 Ivan Soldatović , Damir Radončić , Biljana Šeha , Dragana Jovanović , Milan Savić , Natalija Samardžić , Aleksandra Klisic , Jelena Kotur Stevuljević , Milija Gajić , Marina Roksandić Milenković , ... Pogledajte sve

Walter de Gruyter GmbH

Machine learning methods for landslide mapping studies: A comparative study of SVM and RF algorithms in the Oued Aoulai watershed (Morocco)

Abstract Effective management of watershed risks and landslides necessitates comprehensive landslide susceptibility mapping. Support vector machine (SVM) and random forest (RF) machine learning models were used to map the landslide susceptibility in Morocco’s Taounate Province. Detailed landslide inventory maps were generated based on aerial pictures, field research, and geotechnical survey reports. Factor correlation analysis carefully eliminated redundant factors from the original...

Preuzmite dokument 2025 Velibor Spalevic , Mohamed Mastere , Shuraik Kader , Latifa Ladel , Branislav Dudic

Informa UK Limited

Treatment options for heart failure in individuals with overweight or obesity: a review

Preuzmite dokument 2025 Paschalis Karakasis , Efstratios Karagiannidis , Nikolaos Fragakis , Theocharis Koufakis , Christos Kofos , Athina Nasoufidou , Aleksandra Klisic , Djordje S. Popovic , Panagiotis Stachteas , Dimitrios Patoulias

MDPI AG

Fungal Pathogens Associated with Tomicus Species in European Forests: Regional Variations and Impacts on Forest Health

Pinus species are extensively abundant in Europe and, as pioneer trees, prominently influence local ecology. However, pine forests in Lithuania, Montenegro, and Ukraine have been significantly damaged by pine bark beetles (Tomicus sp.), which are closely associated with ophiostomatoid and other pathogenic fungi. This study aimed to identify the diversity of ophiostomatoid and other fungi associated with Tomicus sp. in these three countries. Fungi were isolated from beetles and identified. High-throughput...

Preuzmite dokument 2025 Rimvydas Vasaitis , Adas Marčiulynas , Valentyna Dyshko , Denys Baturkin , Jelena Lazarević , Audrius Menkis , Malin Elfstrand , Kateryna Davydenko

MDPI AG

Exploring the Potential of Posidonia oceanica Fibers in Eco-Friendly Composite Materials: A Review

The growing demand for sustainable materials has driven the exploration of natural fibers as eco-friendly alternatives to synthetic reinforcements for composites. This study investigates the potential of Posidonia oceanica, an abundant marine biomass, which is often driven to be stacked on the backshore and used so far for energy recovery and low-value applications, as a filler and possible reinforcement in cementitious and polymer composites. Most applications of Posidonia are concentrated in the...

Preuzmite dokument 2025 Ana Pešić , Carlo Santulli , Sara Mattiello , Ana Pavlović , Cristiano Fragassa

MDPI AG

New Evidence for the Contemporary Presence of Juvenile White Sharks (Carcharodon carcharias) in the Adriatic Sea

The presence of the white shark (Carcharodon carcharias) in the Mediterranean Sea is well documented, but mainly through historical and opportunistic records. Historically, the Adriatic Sea, particularly its eastern coastline, was considered a hotspot for white sharks, with relatively frequent reports of juvenile specimens suggesting a potential nursery area. However, since the second half of the 20th century, the abundance of white sharks in the Adriatic has experienced a dramatic decline, with...

Preuzmite dokument 2025 Julia Türtscher , Jürgen Kriwet , Simone Niedermüller , Mišo Pavičić , Ilija Ćetković , Patrick L. Jambura , Pero Ugarković

MDPI AG

GIS-Based Spatial Modeling of Soil Erosion and Wildfire Susceptibility Using VIIRS and Sentinel-2 Data: A Case Study of Šar Mountains National Park, Serbia

Soil erosion and wildfires are frequent natural disasters that threaten the environment. Identifying and zoning susceptible areas are crucial for the implementation of preventive measures. The Šar Mountains are a national park with rich biodiversity and various climate zones. Therefore, in addition to protecting the local population from natural disasters, special attention must be given to preserving plant and animal species and their habitats. The first step in this study involved collecting and...

Preuzmite dokument 2025 Tanja Srejić , Vojislav Deđanski , Aleksandar Valjarević , Filip Vujović , Tin Lukić , Uroš Durlević , Bojana Aleksova

Wiley

Sodium‐glucose cotransporter 2 inhibitors and outcomes in transthyretin amyloid cardiomyopathy: Systematic review and meta‐analysis

AbstractBackgroundTransthyretin amyloid cardiomyopathy (ATTR‐CM) commonly leads to heart failure but has traditionally been an exclusion criterion in randomized clinical trials (RCTs) of sodium‐glucose cotransporter 2 inhibitors (SGLT2i); therefore, the effects of these drugs in this population remain undocumented. In light of recent studies, this meta‐analysis aimed to investigate the effect of SGLT2i on the prognosis of patients with ATTR‐CM.MethodsA comprehensive search of Medline, Scopus, and...

Preuzmite dokument 2025 Paschalis Karakasis , Panagiotis Theofilis , Manfredi Rizzo , Nikolaos Fragakis , Panayotis K Vlachakis , Aleksandra Klisic , Dimitrios Patoulias , Art Schuermans

MDPI AG

Expression Analysis of Circulating miR-21, miR-34a and miR-122 and Redox Status Markers in Metabolic Dysfunction-Associated Steatotic Liver Disease Patients with and Without Type 2 Diabetes

Metabolic dysfunction-associated steatotic liver disease (MASLD), a hepatic form of metabolic syndrome, often co-occurs with type 2 diabetes (T2D) and now affects approximately 30% of the global population. MASLD encompasses conditions from simple steatosis to metabolic dysfunction-associated steatohepatitis, with oxidative stress (OS) driving progression through inflammation. This study analyzes the expression levels of circulating miRNAs and redox status markers in MASLD patients with and without...

Preuzmite dokument 2025 Sanja Erceg , Sanja Vujcic , Miron Sopić , Miloš Mitrović , Jelena Kotur-Stevuljevic , Aleksandra Klisic , Milica Mamić , Ana Ninic , Jelena Munjas , Ratko Tomašević